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Damage Markers - List of Manufacturers, Suppliers, Companies and Products

Damage Markers Product List

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Lipid oxidation damage marker "MDA measurement kit (TBARS method)"

The required time is approximately 1.5 hours! A representative lipid peroxidation marker!

The "MDA Measurement Kit (TBARS Method)" is a marker for measuring lipid oxidation damage through the detection of malondialdehyde. This product reacts malondialdehyde in the sample with thiobarbituric acid (TBA) to form the MDA-TBA2 adduct. Since this adduct has a strong absorption near a wavelength of 532 nm, it allows for the spectroscopic detection of MDA. 【Features】 ■ A marker for measuring malondialdehyde as a lipid oxidation damage indicator ■ Reacts malondialdehyde with thiobarbituric acid (TBA) ■ Forms the MDA-TBA2 adduct ■ Spectroscopically detects MDA *For more details, please refer to the PDF document or feel free to contact us.

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Protein oxidation damage marker "Plasma nitrotyrosine measurement kit"

Measurement of nitrosylated modified proteins using sandwich ELISA method!

The "Plasma Nitrotyrosine Measurement Kit" is a protein oxidation damage marker that can measure nitrosylated modified proteins using the sandwich ELISA method. Nitrotyrosine (3-nitrotyrosine: 3-NT) is one of the major protein nitrosylation modifications caused by peroxynitrite and is widely used as a marker of nitrosative stress. *For more details, please refer to the PDF document or feel free to contact us.*

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Lipid oxidation damage marker "Urinary Isoprostane Measurement Kit"

Introducing an ELISA kit that can measure isoprostanes in urine!

The "Urinary Isoprostane Measurement Kit" is an ELISA kit designed to measure 15-isoprostane F2t (15-isoprostane F2t: 8-epi-PGF2α/8-isoPGF2α) in urine samples. By measuring urinary isoprostanes, it is possible to non-invasively assess oxidative stress (lipid oxidation) in the body. Additionally, we also offer "Urinary Isoprostane Contract Testing" that can accommodate animal samples. *For more details, please refer to the PDF document or feel free to contact us.

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Lipid oxidation damage marker "Hexanoyl Lysine Measurement Kit"

A biomarker that captures the early stages of lipid peroxidation! Quantification of hexanoyl lysine adducts is possible.

This product is expected to serve as a new oxidative stress biomarker that can capture the early stages of lipid peroxidation, unlike conventional aldehyde-based lipid peroxidation markers such as 4-HNE (4-hydroxy-2-nonenal) and MDA (malondialdehyde). Regarding its association with diseases, it has been immunologically proven to localize in human atherosclerotic lesions, and the generation of HEL in muscle in a rat exercise model, as well as the inhibitory effects of flavonoids on its production, have been clarified. 【Features】 ■ Simple quantification of hexanoyl lysine adducts in biological samples ■ Usable for research and evaluation of oxidative stress in vivo, particularly in the early stages of lipid peroxidation ■ Capable of assessing lipid-related oxidative stress in various samples such as urine, serum, and cultured cells *For more details, please refer to the PDF document or feel free to contact us.

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Protein oxidation damage marker "Carbonylated protein measurement kit"

Highly sensitive measurement of carbonylated proteins! Reagents for oxidative stress research!

The "Carbonylated Protein Measurement Kit" is a marker for protein oxidative damage in humans and animals. Traditionally, colorimetric methods and HPLC methods utilizing the reaction with dinitrophenylhydrazine (DNPH) have been used to measure carbonylated proteins, but there have been issues such as the need for a large sample volume. This kit allows for the high-sensitivity measurement of carbonylated proteins by reacting the carbonylated proteins in the sample with DNPH and then using a specific antibody that binds to the DNPH-conjugated proteins. 【Features】 ■ Reacts carbonylated proteins in the sample with DNPH ■ Uses a specific antibody for DNPH-conjugated proteins ■ Measures carbonylated proteins *For more details, please refer to the PDF document or feel free to contact us.

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Protein oxidation damage marker "Dityrosine (DT) measurement kit"

Simple measurement of dihydroxyphenylalanine in the sample! ELISA kit!

The "Dityrosine (DT) Measurement Kit" is an ELISA kit that allows for the simple measurement of dityrosine in samples. Dityrosine is a dimer of tyrosine formed by the oxidation of tyrosine in proteins or free tyrosine. It is formed with tyrosyl radicals as intermediates through ultraviolet light, radiation, hydrogen peroxide, and peroxidase. In addition to being detected in atherosclerotic lesions, it has also been found in connective tissues such as collagen and elastin. Dityrosine can also be detected in urine and is expected to be a new protein oxidation marker that can be measured non-invasively. *For more details, please refer to the PDF document or feel free to contact us.*

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Lipid oxidation damage marker "Oxidized LDL measurement kit"

A lipid oxidation damage marker that can measure oxidized LDL! The required time is approximately 5.5 hours.

The "Oxidized LDL Measurement Kit" is a lipid oxidation damage marker that can measure oxidized LDL in human serum/plasma samples. The measurement principle is the sandwich ELISA method. The required time is approximately 5.5 hours. *For more details, please refer to the PDF document or feel free to contact us.

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Lipid oxidation damage marker "Isoprostane measurement kit"

It is possible to non-invasively assess oxidative stress in vivo!

We would like to introduce our lipid oxidation damage marker, the "Isoprostane Measurement Kit." By measuring isoprostanes in urine, it is possible to non-invasively evaluate oxidative stress (lipid oxidation) in the body. This product is an ELISA kit designed to measure 15-isoprostane F2t in urine samples. 【Product Specifications (Partial)】 ■ Measurement Principle: Competitive ELISA Method ■ Measurement Target: Urinary Isoprostanes ■ Measurement Range: 0.05 to 100 ng/mL ■ Time Required: Approximately 3 hours ■ Sample Volume Required: Approximately 100 μL *For more details, please download the PDF or feel free to contact us.

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DNA oxidative damage marker '8-OHdG Check ELISA'

Easily and sensitively measurable 8-OHdG in urine, serum, and tissue DNA!

The "8-OHdG Check ELISA" is an ELISA kit that uses a monoclonal antibody (N45.1) specific to 8-hydroxy-2'-deoxyguanosine. It allows for easy and sensitive measurement of 8-OHdG in urine, serum, and tissue DNA. It reacts very little with the RNA oxidant 8-hydroxy-guanosine (8-OHG) and is characterized by its ability to specifically detect the DNA oxidant (8-OHdG). In particular, the "New 8-OHdG Check" is designed for urinary 8-OHdG and can measure multiple samples of urinary 8-OHdG within 3 hours without any pretreatment. 【Product Specifications (Excerpt)】 ■ Measurement Range: 0.5 to 200 ng/mL ■ Specificity: Specifically detects 8-OHdG ■ Capacity: 96 wells for 18 samples (N=3 measurements) ■ Storage Conditions: Refrigerated (2 to 8°C); please use within 2 weeks after opening *For more details, please download the PDF or feel free to contact us.

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Protein oxidation damage marker "Plasma nitrotyrosine measurement kit"

Jichiroshin can also be detected in urine! Applicable to both humans and animals.

The "Plasma Nitrotyrosine Measurement Kit" is an ELISA kit that allows for the simple measurement of dityrosine in samples. Dityrosine is formed as an intermediate through tyrosyl radicals by ultraviolet light, radiation, hydrogen peroxide, and peroxidase. It is detected not only in atherosclerotic lesions but also in connective tissues such as collagen and elastin. Dityrosine is also detectable in urine and is expected to serve as a new non-invasive protein oxidation marker. 【Product Specifications (Partial)】 ■ Measurement Targets: Serum, plasma, feces (applicable to both humans and animals) ■ Specificity: Nitrolysed modified proteins ■ Measurement Range: 55.5 to 1500 nM ■ Time Required: Approximately 4 hours ■ Sample Volume Required: 50 μL *For more details, please download the PDF or feel free to contact us.

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